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A sodium hyaluronate is naturally present in large quantities in the synovial fluid, which protects and lubricates the joints during movement. EUFLEXXA is prescribed for patients with osteoarthritis for the treatment of knee pain and inflammation. EUFLEXXA is used in patients with osteoarthritis who have already tried non-pharmacological treatments such as diet, exercise and pharmacological therapies, such as pain medication, but they do not show any notable results.
The knee is protected from injuries and strokes due to the presence of synovial fluid in the knee joints. Synovial fluid acts as a lubricant and cushion with viscous and rheological properties due to the presence of sodium hyaluronate. With the loss of synovial fluid, protection is lost, and this leads to knee osteoarthritis and pain. EUFLEXXA synovial fluid provides relief from knee pain for up to six months.
A synovial fluid that is viscoelastic due to the presence of hyaluronic acid is found in all synovial joints, particularly in heavy load bearing joints, where it provides normal painless movement due to its lubricating and damping properties. It is also responsible for cartilage operating.
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In the case of disorders associated with damaged joints, for example, osteoarthrosis, the viscoelasticity of the synovial fluid is significantly reduced, which reduces the lubricating and damping functions. This leads to an increase in the mechanical load on the joint and damaging of the cartilage, which ultimately leads to pain and limited mobility of that joint.
Adding synovial fluid EUFLEXXA by intraarticular injection of highly purified hyaluronic acid can increase the viscoelastic properties of the synovial fluid. This increases the lubricating and damping functions and reduces the mechanical stress on the joint. Typically, this leads to a reduction in pain and increased joint mobility, which can last for at least several months after the treatment cycle, which usually involves five intraarticular injections.
Sterile filled syringe containing 20 mg / 2 ml of sodium hyaluronate as an isotonic solution in a sterile sac.
To sum up, intra-articular injection of EUFLEXXA is indicated for pain and limited mobility in degenerative-dystrophic and traumatic changes of the hip, knee joint and other synovial joints.
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